Table 1 Metrics of different ANN methods (MIL with attention (MIL-attention), MIL with maxpooling (MIL-max), MIL with mean pooling (MIL-mean), and the baseline SELU CNN (baseline SELU)).
Data type | Method | Accuracy | F1-score | AUC | Sensitivity | Specificity |
|---|---|---|---|---|---|---|
tiles | MIL-attention | 0.95 (0.94–0.96) | 0.97 (0.96–0.97) | 0.99 (0.99–0.99) | 0.96 (0.95–0.97) | 0.93 (0.90–0.95) |
tiles | MIL-max | 0.90 (0.89–0.92) | 0.93 (0.92–0.94) | 0.96 (0.96–0.96) | 0.94 (0.91–0.98) | 0.78 (0.69–0.87) |
tiles | MIL-mean | 0.88 (0.87–0.89) | 0.92 (0.91–0.92) | 0.91 (0.91–0.92) | 0.93 (0.92–0.95) | 0.72 (0.69–0.75) |
downscaled WSIs | baseline SELU | 0.76 (0.72–0.80) | 0.83 (0.78–0.87) | 0.84 (0.82–0.86) | 0.78 (0.68–0.87) | 0.73 (0.57–0.89) |