Table 4 Tumor bed changes related to breast tumor subtype.

From: Clinico-pathologic predictors of patterns of residual disease following neoadjuvant chemotherapy for breast cancer

 

HR+/HER2−

(n = 242)

HER2+

(n = 216)

TNBC

(n = 207)

p value

Fibrosis/scarring

241 (99.6%)

209 (96.8%)

206 (99.5%)

0.014

Foamy macrophages

39 (16.1%)

60 (27.8%)

67 (32.4%)

<0.001

Hemosiderin laden-macrophages

110 (45.5%)

110 (50.9%)

136 (65.7%)

<0.001

Hemosiderin deposition

132 (54.5%)

106 (49.1%)

146 (70.5%)

<0.001

Stromal elastosis

94 (38.8%)

67 (31.0%)

51 (24.6%)

0.005

Myxoid change

46 (19.0%)

29 (13.4%)

17 (8.2%)

0.004

Stromal mucin

20 (8.3%)

11 (5.1%)

1 (0.5%)

0.001

  1. HR hormone receptor, TNBC triple negative breast cancer.