Table 1 IHC, RT-PCR and FISH data from single sections of RMS tumors.
Age | Sex | Localization | PFM.2 (IHC) | RT-PCR | FOXO1 rearrangement (FISH)a | AP2β (IHC) | Histological diagnosis |
|---|---|---|---|---|---|---|---|
45 y | m | Parotis | 30% | PAX3-FOXO1 | Detected | 80% | ARMS |
23 y | m | Testis | 50% | PAX3-FOXO1 | Detected | 80% | ARMS |
25 y | w | Mamma | 80% | PAX3-FOXO1 | Detected | >90% | ARMS |
1.5 y | m | Eye lid | 30% | PAX3-FOXO1 | Detected | 50% | ARMS |
19 y | m | Hand | 80% | PAX3-FOXO1 | Detected | 80% | ARMS |
17 y | m | Metastasis (bone) | >90 % | PAX3-FOXO1 | Detected | >90% | ARMS |
30 y | w | Nasal cavity | >90 % | PAX3-FOXO1 | Detected | 80% | ARMS |
20 y | m | Testis | <5 % | PAX3-FOXO1 | Detected | 50% | ARMS |
20 y | m | Anus | 80% | PAX3-FOXO1 | Detected | >90% | ARMS |
3 y | M | Trunk | 30% | PAX3-FOXO1 | Detected | >90% | ARMS |
23 y | m | Sinus maxillaris | >90 % | PAX3-FOXO1 | Detected | 80% | ARMS |
18 y | m | Metastasis (lymph node inguinal) | 20% | PAX3-FOXO1 | Detected | >90% | ARMS |
31 y | m | Nasal cavity | 50% | Not Available | Detected | >90% | ARMS |
9 m | w | Sacrum | <5 % | PAX7-FOXO1 | Detected (with co-amplification) | >90% | ARMS |
16 y | m | Lower leg | >90 % | PAX7-FOXO1 | Not detected | >90% | ARMS |
5.5 y | w | Trunk | 50% | PAX7-FOXO1 | Detected (with co-amplification) | 50% | ARMS |
12 y | w | Trunk | <5 % | PAX7-FOXO1 | Detected (with co-amplification) | >90% | ARMS |
3 y | m | Lower leg | <5 % | PAX7-FOXO1 | Detected (with co-amplification) | 50% | ARMS |
9 m | w | Trunk | Negative | Negative | Negative | 80% | Fusion-negative ARMS |
20 y | m | Paratesticular | Negative | Negative | Negative | <5% | Fusion-negative ARMS |
53 y | m | Tongue | Negative | Negative | Negative | Negative | Pleomorphic RMS |
2 m | m | Eye | Negative | Negative | Not Available | <5% | ERMS |
2 y | w | Parotis | Negative | Negative | Negative | Negative | ERMS |
6 y | m | Sinus maxillaris | Negative | Negative | Negative | <5% | ERMS |
17 y | w | Metastasis (lung) | Negative | Negative | Negative | <5% | ERMS |
6 y | w | Neck | Negative | Negative | Negative | Negative | ERMS |
