Table 3 IHC data from staining of 26 RMS single whole sections and tissue micro array (including 127 additional RMS) with mAb PFM.2.

From: Immunohistochemical detection of PAX-FOXO1 fusion proteins in alveolar rhabdomyosarcoma using breakpoint specific monoclonal antibodies

 

PAX-FOXO1 fusion-positive RMS

ERMS and PAX-FOXO1 fusion-negative RMSa

PFM.2 IHC positive

29

0

PFM.2 IHC negative

3

121

 

Sensitivity = 0.91

Specificity = 1

 

Positive predictive value = 1

Negative predictive value = 0.98

  1. aInclude 112 embryonal RMS (ERMS), 8 fusion-negative alveolar RMS, and one pleomorphic RMS.
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