Fig. 1: Stratification of specimens by preanalytic variables. | Modern Pathology

Fig. 1: Stratification of specimens by preanalytic variables.

From: Targeted massively parallel sequencing of mature lymphoid neoplasms: assessment of empirical application and diagnostic utility in routine clinical practice

Fig. 1

Preanalytic variables among processed MLN specimens (n = 534) that include specimens inadequate for sequencing due to QTF or QLF, excluding non-MLN cases (n = 23) and cases in which tumor percent was not reported or not calculable (n = 26) yielding 485 MLN cases with calculable tumor percentages. Noted in parentheses is the number of extramural (EM) cases. There were no extramural fresh specimens. To facilitate statistical analysis, specimen types were grouped based on overall expected tissue quantity. “Core Bx” includes mostly core biopsies (including a single decalcified bone marrow core biopsy [see Table 1 footnote f for more detail]), seven punch biopsies, and a single FNA cell block. “Excisional Bx” includes mostly excisional biopsies of lymph nodes as well as larger excisions of extranodal tissue and a single wedge biopsy of lung tissue. “Other Fresh” includes lymph node FNA (n = 2), extranodal FNA (n = 1), and other body fluid specimens (n = 3).

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