Fig. 5: Distribution of DAVs present in major small B-cell lymphoma categories. | Modern Pathology

Fig. 5: Distribution of DAVs present in major small B-cell lymphoma categories.

From: Targeted massively parallel sequencing of mature lymphoid neoplasms: assessment of empirical application and diagnostic utility in routine clinical practice

Fig. 5

The five most frequent small B-cell lymphoma categories are shown with the frequency of DAVs in each gene per category represented as a percentage of the total cases per category. 10 of the 12 cases of lymphoplasmacytic lymphoma had a mutation in MYD88 (83%), while one-third had DAVs of CXCR4. The most frequent DAVs in cases of MCL were TP53 (18%), ATM (14%), and BIRC3 (7%), while the most frequent DAVs in cases of follicular lymphoma were CREBBP (28%), EZH2 (21%), and TNFRSF14 (19%). Cases of marginal zone lymphoma most frequently had DAVs in TNFAIP3 (15%) and NOTCH2 (12%).

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