Table 3 Cox regression for overall and disease-free survival using only tumor type and ASCO–CAP 2018 ISH Groups.

From: Clinical significance of quantitative categorization of HER2 fluorescent in situ hybridization results in invasive breast cancer patients treated with HER2-targeted agents

Prognostic variable

Hazard ratio

Lower .95

Upper .95

p value

Overall survival

 Tumor type

2.180

1.345

3.532

0.0015

 ASCO–CAP ISH Groups

1.296

1.111

1.513

0.0010

Disease-free survival

 Tumor type

1.837

1.111

3.040

0.0178

 ASCO–CAP ISH Groups

1.325

1.136

1.546

0.0003

  1. ASCO–CAP American Society of Clinical Oncology–College of American Pathologist, ISH in situ hybridization.