Table 1 Clinicopathological and Molecular findings.
From: Recurrent novel THBS1-ADGRF5 gene fusion in a new tumor subtype “Acral FibroChondroMyxoid Tumors”
ID | Initial diagnosis | Age/gender | Location | Fusion type | Sample type | Bone involvement | Treatment | Follow-up (months) |
|---|---|---|---|---|---|---|---|---|
Case 1 | Chondroma or chondromyxoid fibroma | 20/F | Foot (left T3) | THBS1(e21)-ADGRF5(e12) | Recurrence | Yes | Surgery | NA |
Case 2 | 48/M | Hand (left P1) | THBS1(e21)-ADGRF5(e12) | Primary | No | Surgery | NED (14) | |
Case 3 | Chondromyxoid fibroma | 36/M | Foot (left T2 P3) | THBS1(e21)-ADGRF5(e12) | Primary | Yes | Surgery | NED (42) |
Case 4 | Acral fibromyxoma | 37/M | Hand (left D2 Metacarpophalangeal joint) | THBS1(e21)-ADGRF5(e12) | Primary | Yes | Surgery | NED (21) |
Case 5 | Soft-tissue chondroma | 64/M | Hand (right D3) | THBS1(e21)-ADGRF5(e12) | Primary | No | Surgery | NED (13) |
Case 6 | Soft-tissue chondroma | 45/F | Hand (D3 P1) | THBS1(e21)-ADGRF5(e12) | Primary | No | Surgery | NED (12) |
Case 7 | Soft-tissue chondroma | 58/M | Capsula of right metacarpophalangeal joint of D4 | THBS1(e21)-ADGRF5(e9) | Primary | Yes | Surgery | NED (26) |
Case 8 | Acral fibromyxoma | 50/M | Foot (right T2) | THBS1(e21)-ADGRF5(e12) | Primary | No | Surgery | NED (32) |
Case 9 | Myoepithelioma | 24/M | Hand (D2 P3) | THBS1(e21)-ADGRF5(e12) | Primary | Yes | Surgery | NED (3) |
Case 10 | Myoepithelioma | 37/F | Hand (D3 P3) | THBS1(e21)-ADGRF5(e12) | Recurrence | No | Surgery | NED (14) |
