Table 2 The literature review of soft tissue aneurysmal bone cyst.
Reference | Number of cases | Patient demographics and tumor location | Treatment and follow-up | Molecular analyses |
|---|---|---|---|---|
Amir et al. [20] | 1 | 15/F, groin | Excised with no recurrence | NP |
Rodríguez-Peralto et al. [21] | 1 | 20/F, shoulder | N/A | NP |
López-Barea et al. [22] | 1 | 57/F, upper arm | Excised with no recurrence | NP |
Shannon et al. [23] | 1 | 29/F, retro-clavicular | Excised with no recurrence | NP |
Nielsen et al. [24] | 5 | 8/M, shoulder; 29/F, groin; 37/F, upper arm; 28/M, upper arm; 30/F, thigh | Excised with no recurrence | 8/M, shoulder−t(17;17)(p13;q12) COL1A1-USP6 fusion [5] |
Wang et al. [25] | 1 | 21/M, gluteus | Excised with no recurrence | NP |
Ajilogba et al. [26] | 1 | 12/F, thigh | Excised with no recurrence | NP |
Ellison et al. [27] | 1 | 10/F, thigh | Excised with no recurrence | t(5;17)(q33;p13) |
Sukov et al. [10] | 2 | 11/M, thigh; 36/F, thigh | N/A | Both showed USP6 rearrangement |
Pietchmann et al. [28] | 2 | 26/F, thigh; 38/M, upper arm | Excised with no recurrence | Both showed USP6 rearrangement |
Hao et al. [29] | 1 | 10/F, shoulder | Excised with no recurrence | NP |
Baker et al. [30] | 1 | 41/F, upper arm | Excised with no recurrence | NP |
Jacquot et al. [31] | 1 | 46/F, thigh | Excised with no recurrence | t(17;17)(p13;q21) COL1A1-USP6 fusion |
Bekers et al. [11] | 11 | 24/F, perineum; 19/F, leg; 28/M, arm; 44/M, thoracic wall; 25/M, thigh; 17/F, thigh; 38/F, thigh; 32/F, thigh; 8/F, knee; 56/M, thigh; 6/F, gluteus | N/A | 8/11 cases showed USP6 rearrangement; 1/11 showed no USP6 rearrangement; 2/11 N/A |
Švajdler et al. [12] | 15 | 44/M, thigh; 22/F, thigh; 28/M, gluteus; 35/F, thigh; 53/M, scapula; 10/M, neck; 35/M, thigh; 52/F, thigh; 19/F, arm; 31/M, thigh; 46/F, thigh; 37/F, arm; 60/M, thigh; 62/M, arm; 6/M, abdominal wall | N/A | 5/15 showed COL1A1-USP6 fusion; 2/15 showed no USP6 rearrangement on sequencing; 8/15 N/A |
Song et al. [13] | 6 | 49/F, thigh; 34/F, thigh; 15/M, thigh; 19/F, thigh; 16/F, abdominal wall; 32/M, gluteus | Excised with no recurrence | 3/6 cases showed COL1A1-USP6 fusion; 1 additional case showed USP6 rearrangement; 2/6 cases failed FISH and RNA sequencing studies |
Our series | 7 | 32/F, thigh; 17/M, supraclavicular soft tissue; 46/F, gluteus; 51/F, hand; 22/F, axilla; 14/F, thigh; 41/M, thigh | 3/7 excised with no recurrence; 3/7 clinically stable; 1/7 lost to follow-up | 6/7 cases showed COL1A1-USP6 fusion; 1/7 case showed ANGPTL2-USP6 fusion |
