Fig. 1: Cases PT1 and PT2 and their mutations. | Modern Pathology

Fig. 1: Cases PT1 and PT2 and their mutations.

From: Morphologic and genetic heterogeneity in breast fibroepithelial lesions—a comprehensive mapping study

Fig. 1

Light microscopy images at low magnification show malignant PT regions (a, b) of case PT1, and a more “benign PT” appearing component (c); and of case PT2’s borderline PT (d) diagnosed in 2007, and spindle cell metaplastic carcinoma (e) in 2013. The latter shows diffuse cytoplasmic MNF116 immunoreactivity. The tables reflect their corresponding mutations and variant allele frequencies (darker shades of red reflect higher VAF, closer to 100%; darker shades of blue reflect lower VAF, closer to 0%). Phylogenetic trees indicate genes mutated in all samples (blue), those mutated in at least two samples (green), and those mutated in one sample (red).

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