Table 2 Hormone receptors, HER2 immunohistochemistry (IHC), and fluorescence in situ hybridization (FISH) results.
From: Histopathologic features of breast cancer in Li–Fraumeni syndrome
Case | Histology | ER (%) | PR (%) | HER2 IHC | HER2 FISH | ||
|---|---|---|---|---|---|---|---|
Results | HER2 copy number | HER2/CEP17 ratio | |||||
1 | DCIS | 95 | 70 | 0 | Negative | 2.0 | 1.0 |
2 | DCIS | 95 | 30 | 0 | Negative | 2.0 | 1.1 |
3 | DCIS | 50 | 0 | 2+ | Positive | 7.9 | 2.7 |
4 | DCIS mi | 0 | 0 | 3+ | Positive | 21.6 | 12.7 |
5 | DCIS | 0 | 0 | 3+ | Positive | 19.1 | 10.6 |
6 | DCIS | 50 | 70 | 3+ | Positive | 7.9 | 4.5 |
7 | DCIS | N/A | N/A | N/A | N/A | N/A | N/A |
8 | DCIS mi | 0 | 0 | 3+ | Positive | 10.8 | 2.7 |
9 | DCIS | 0 | 0 | 3+ | N/A | N/A | N/A |
10 | IDC | 90 | 40 | 0 | N/A | N/A | N/A |
11 | IDC | 95 | 70 | 1+ | Positive | 4.9 | 2.3 |
12 | IDC | 10 | 1 | 3+ | Positive | 15.7 | 8.1 |
13 | IDC | 95 | 25 | 3+ | N/A | N/A | N/A |
14 | IDC | 80 | 10 | 0 | Negative | N/A | N/A |
15 | IDC | 95 | 95 | 0 | Negative | 1.9 | 1.1 |
16 | IDC | 95 | 95 | 0 | Negative | 2.0 | 0.25 |
17 | IDC | 95 | 80 | 0 | Negative | 1.9 | 1.1 |
18 | IDC | 70 | 95 | 3+ | Positive | 10.6 | 5.8 |
19 | IDC | 95 | 95 | 0 | N/A | N/A | N/A |
20 | IDC | 50 | 10 | 3+ | Positive | N/A | N/A |
21 | IDC | 40 | 60 | 3+ | Positive | 16.2 | 6.7 |
22 | IDC | 0 | 0 | 0 | Negative | 1.9 | 1.1 |
23 | IDC | 70 | 0 | 3+ | Positive | 14.7 | 7.7 |
24 | IDC | 90 | 95 | 1+ | Positive | 8.4 | 4.8 |
25 | IDC | 5 | 0 | 3+ | Positive | 12.1 | 6.7 |
26 | IDC | N/A | N/A | N/A | N/A | N/A | N/A |
27 | IDC | 95 | 40 | 0 | Negative | 4.1 | 1.3 |
