Table 4 P53 immunohistochemistry (IHC) in tumor tissue and correlation with germline mutation.
From: Histopathologic features of breast cancer in Li–Fraumeni syndrome
P53 IHC in tumor cells | |||
|---|---|---|---|
<1% | 1–50% | >50% | |
Germline mutation | |||
Missense | 0 | 4 | 9 |
Nonsense | 6 | 0 | 0 |
Deletion | 2 | 0 | 0 |
Splice | 2 | 0 | 0 |
N/A | 1 | 0 | 1 |
Total | 11 | 4 | 10 |
