Fig. 2: Low-grade spindle-cell neoplasms with NTRK1 rearrangements. | Modern Pathology

Fig. 2: Low-grade spindle-cell neoplasms with NTRK1 rearrangements.

From: Mesenchymal tumors of the gastrointestinal tract with NTRK rearrangements: a clinicopathological, immunophenotypic, and molecular study of eight cases, emphasizing their distinction from gastrointestinal stromal tumor (GIST)

Fig. 2

a Monomorphic spindle-cell population with intracytoplasmic vacuoles (b), mimicking lipoblasts or GIST cells (case 5). c Storiform pattern of growth, focally reminiscent of dermatofibrosarcoma protuberans (case 6); in other areas of the same tumor, long fascicles of spindle cells resembling desmoid or low-grade MPNST (d).

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