Fig. 3: High-grade spindle-cell sarcomas with NTRK1 rearrangements. | Modern Pathology

Fig. 3: High-grade spindle-cell sarcomas with NTRK1 rearrangements.

From: Mesenchymal tumors of the gastrointestinal tract with NTRK rearrangements: a clinicopathological, immunophenotypic, and molecular study of eight cases, emphasizing their distinction from gastrointestinal stromal tumor (GIST)

Fig. 3

a Highly infiltrative malignant spindled cell tumor (case 7). Some areas showed myxoid stroma generating an epithelioid or round-cell morphology (b). Case 8 demonstrated transition from low-grade spindle-cell areas (c) to high-grade areas resembling pleomorphic sarcoma (d).

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