Fig. 4: Immunophenotype of gastrointestinal mesenchymal tumors with NTRK1 rearrangements. | Modern Pathology

Fig. 4: Immunophenotype of gastrointestinal mesenchymal tumors with NTRK1 rearrangements.

From: Mesenchymal tumors of the gastrointestinal tract with NTRK rearrangements: a clinicopathological, immunophenotypic, and molecular study of eight cases, emphasizing their distinction from gastrointestinal stromal tumor (GIST)

Fig. 4

TRK expression was diffused in all cases with variable intensity: cytoplasmic staining of strong intensity shown in case 7 (a) and moderately strong cytoplasmic staining in case 1 (b). CD34 (c) and S100 (d) were coexpressed in three tumors (case 6). SOX10 immunohistochemistry was consistently negative.

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