Table 2 Pathological findings of cervical carcinomas with serous-like features.
Case | Serous-like morphological pattern | Percentage of serous-like (papillary/micropapillary) component | Coexisting AIS | Coexisting HSIL | Silva patterna | LVIa | PNIa | Lymph node metastasisa | Other pathologic findings |
|---|---|---|---|---|---|---|---|---|---|
HPV-associated cervical carcinomas with serous-like features (cases 1–10) | |||||||||
1 | Papillary | 80 | Usual-type AIS | – | B | – | – | – | |
2 | Papillary | 100 | – | – | |||||
3 | Papillary | 100 | – | – | C | – | – | – | |
4 | Papillary | 60 | – | HSIL | C | + | – | – | |
5 | Papillary | 100 | Usual-type AIS | HSIL | B | – | – | – | |
6 | Micropapillary | 100 | – | HSIL | C | ||||
7 | Micropapillary | 20 | Usual-type AIS | – | C | + | – | – | |
8 | Micropapillary | 10 | Usual-type AIS | – | C | – | – | – | |
9 | Papillary | 70 | – | – | C | – | – | + (bilateral pelvic and para-aortic lymph nodes) | |
10 | Micropapillary | 90 | – | HSIL | C | + | – | ||
HPV-independent cervical carcinomas with serous-like features (cases 11–14) | |||||||||
11 | Papillary | 80 | – | – | |||||
12 | Micropapillary | 10 | Gastric-type AIS | – | + | – | Lobular endocervical glandular hyperplasia | ||
13 | Micropapillary | 20 | Gastric-type AIS | – | + | + | + (bilateral pelvic lymph nodes) | Venous invasion; involvement of endometrium | |
14 | Micropapillary | 30 | – | – | |||||
