Fig. 2: Representative H&E and immunohistochemical staining patterns of immune cell infiltration in anorectal malignant melanoma (ARMM). | Modern Pathology

Fig. 2: Representative H&E and immunohistochemical staining patterns of immune cell infiltration in anorectal malignant melanoma (ARMM).

From: Distribution pattern of tumor infiltrating lymphocytes and tumor microenvironment composition as prognostic indicators in anorectal malignant melanoma

Fig. 2

(Upper column) Absent, non-brisk, and brisk CD3+ T lymphocytic infiltration in ARMM. (Lower column) Immune phenotypes in ARMM. Representative images of CD3 immunohistochemistry showing three patterns of T cells associated with malignant melanoma cells. (Lower left) immune-desert, (Lower middle) immune-excluded, and (Lower right) inflamed phenotype. CD3-positive T cell staining is indicated by the red chromogen. The blue color is the hematoxylin counterstain. Original magnification, ×200 (Inset, H&E).

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