Table 4 Patient and tumor characteristics of the 106 cases used for validation.

From: Prosigna® breast cancer assay: histopathologic correlation, development, and assessment of size, nodal status, Ki-67 (SiNK™) index for breast cancer prognosis

Age in years

Mean: 59.9

Median: 58.5

Range: 38–90

Size in mm

Mean: 15.5

Median: 15

Range: 6–45

Grade

I: 40 (38%)

II: 56 (44%)

III: 25 (18%)

Tumor type

Ductal: 97 (91%)

Lobular: 7 (7%)

Mixed: 2 (2%)

Lymph node status

Negative: 76 (72%)

Positive: 30 (28%)

AJCC anatomic stage

I: 75 (71%)

II: 31 (29%)

Ki-67 labeling index

Mean: 17.5

Median: 11

Range: 1–86

PR status

Negative: 9 (8%)

Positive: 97 (92%)

Systemic therapy

Chemotherapy only: 2 (2%)

Chemo + endocrine therapy: 39 (37%)

Endocrine therapy only: 40 (38%)

None: 8 (7%)

Unknown: 17 (16%)

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