Fig. 4: Venn diagram of neuroendocrine markers expression in IBC-NST.
From: Breast cancer with neuroendocrine differentiation: an update based on the latest WHO classification
The expression of NE markers (Synpatophysin (SYN), Chromogranin (CG), Insulinoma-associated protein 1 (INSM1) and CD56) on a large local cohort of IBC-NST (N = 1217) were analysed by immunohistochemistry on tissue microarray. A cutoff of 1% was applied to define positivity. In total, 239 cases expressed either one of the four markers (NE marker positive case). The percentage in the rectangle represented the expression rate of each marker in the NE marker positive cases. The embedded table showed the expression rate of different NE marker combinations in all IBC-NST or in cases with at least NE marker positivity.
