Fig. 1: Representative hematoxylin and eosin-stained sections of hybrid schwannoma–perineurioma with CHD7-VGLL3 fusion gene.
From: Hybrid schwannoma–perineurioma frequently harbors VGLL3 rearrangement
A Scanning magnification showing a circumscribed and unencapsulated neoplasm centered within the subcutaneous adipose tissue. Note entrapped adnexal structures. B, C Intermediate magnifications demonstrating a spindle cells with a storiform-fascicular pattern. The cytoplasm is pale with indistinct borders. D High magnification revealing two distinct nuclear populations. Many cells have plump ovoid nuclei, while a minority are fusiform and elongated. Only mild, likely degenerative, nuclear atypia is present.
