Fig. 2: Representative hematoxylin and eosin-stained sections of hybrid schwannoma–perineurioma with alternate fusion gene products. | Modern Pathology

Fig. 2: Representative hematoxylin and eosin-stained sections of hybrid schwannoma–perineurioma with alternate fusion gene products.

From: Hybrid schwannoma–perineurioma frequently harbors VGLL3 rearrangement

Fig. 2

Tumors with alternate VGLL3 fusion partners were morphologically and immunophenotypically indistinguishable from those with the more common partner: (A) CHD9-VGLL3 fusion gene, (B) MAMLD1-VGLL3 fusion gene. Similarly, two tumors with altogether different fusion gene products were indistinguishable from those with VGLL3 rearrangement, including cases with a (C) DST-BRAF fusion gene and (D) SQSTM1-CDX1 fusion gene. All images ×400.

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