Fig. 3: Analysis of the ADPR signal intensities in colon cancer. | Modern Pathology

Fig. 3: Analysis of the ADPR signal intensities in colon cancer.

From: Cytoplasmic ADP-ribosylation levels correlate with markers of patient outcome in distinct human cancers

Fig. 3

A IHC staining of a colon cancer TMA using the anti-ADPr antibody. Staining intensity scores: strong (red, 3), moderate (yellow, 2), and weak/negative (blue, 1). On the top, selected TMA cores (scale bar 100 µm, 10x), on the bottom, ROIs (scale bar 20 µm, 40x). Contingency analyses to assess the association between cyADPR scores and (B) the tumor stage (pT 1–4), (C) the tumor grade (1–3), (D) regional lymph node metastasis (pN 0–2), and (E) the presence of distant metastasis (pM 0–1).

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