Fig. 1: Representative images of the radiological (A–C) and gross (D) features of HMGA2-NCOR2 fusion-positive giant cell tumors (Case 2). | Modern Pathology

Fig. 1: Representative images of the radiological (A–C) and gross (D) features of HMGA2-NCOR2 fusion-positive giant cell tumors (Case 2).

From: Recurrent novel HMGA2-NCOR2 fusions characterize a subset of keratin-positive giant cell-rich soft tissue tumors

Fig. 1

Coronal T1-weighted (T1W) pre- (A) and post-contrast (B) and proton-density (C) MR images show an enhancing deep subcutaneous mass that abuts the peripheral fascia at the distal medial aspect of the right thigh. The slight hyperintensity of the tumor relative to muscle on pre-contrast T1W images and the peripheral low signal on all sequences likely represent its hemorrhagic content. Mild reticular edema surrounds the lesion. The epicenter of the tumor is in the subcutaneous tissue with well-circumscribed borders and tan to brown lobulated cut-surface (D).

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