Table 3 Comparison of the main clinicopathological and molecular features of keratin-positive and keratin-negative giant cell-rich tumors of soft tissue.

From: Recurrent novel HMGA2-NCOR2 fusions characterize a subset of keratin-positive giant cell-rich soft tissue tumors

Features

Keratin-positive tumors (n = 6)

Keratin-negative tumors (n = 9)

p value

Age range (mean)

14–60 years (34.7)

11–78 years (46.7)

0.48

Female: male (% females)

5:1 (83%)

4:5 (44.4%)

0.29

Size range cm (mean)

2–3 (2.5)

1.5–4.5 (2.5)

0.71

Mature bone formation (%)

0/6 (0%)

4/9 (44.4%)

0.10

Mitotic range (mean)

1–14 (7.2)

0–17 (4.1)

0.47

Peritumoral lymphoid reaction (%)

4/6 (66.7%)

0/9 (0%)

0.01

HMGA2-NCOR2 fusion

6/6

0/7

0.001

  1. Statistically significant p-values are in bold.
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