Fig. 3: Somatic mutations and copy number alterations identified in the mesonephric-like carcinoma of the ovary mixed with mucinous and serous tumors. | Modern Pathology

Fig. 3: Somatic mutations and copy number alterations identified in the mesonephric-like carcinoma of the ovary mixed with mucinous and serous tumors.

From: Mesonephric and mesonephric-like carcinomas of the female genital tract: molecular characterization including cases with mixed histology and matched metastases

Fig. 3

Representative hematoxylin and eosin-stained sections of separate components of mixed mesonephric-like and mucinous borderline tumors A OV75 and B OV21; and C OV74 mixed mesonephric-like and serous borderline tumor/low-grade serous carcinoma (SBT/LGSC) are shown (left). Corresponding copy number plots are shown (middle) with Log2-ratios on the y-axis and chromosome location on the x-axis. On the right, heatmaps depicting non-synonymous somatic mutations (left) and the cancer cell fractions of the mutations identified (right) in both histological components. Clonal mutations are depicted by a yellow box. Cancer cell fractions are color-coded according to the legend.

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