Table 2 Histopathologic features of the study cases.

From: Re-evaluating tumors of purported specialized prostatic stromal origin reveals molecular heterogeneity, including non-recurring gene fusions characteristic of uterine and soft tissue sarcoma subtypes

Case

Age

Histomorphology

Morphologic patterna

Diagnosis

ABG

Mitoses

Hypercellularity

Necrosis

Atypia

MTC

1

66

Solidb (ESS-like)

Patternless

PSS (IG)

No

15

+++

No

−−

No

2

21

Solidb

Short fascicles

PSS (IG)

Yes

25

+++

No

−−

No

3

30

Solidb

Patternless/Epithelioid

PSS (IG)

No

22

+++

No

−−

No

4

57

Solidb

Epithelioid/Storiform

PSS (HG)

No

14

++

Yes

++

No

5

76

Solidb

Patternless/Epithelioid

PSS (HG)

No

11

+++

Yes

++

Yes

6

60

Solidb

Short fascicles/Storiform

PSS (LG)

No

6

+

No

−−

No

7

32

Solidb

Fibrosarcomatous/Soriform

PSS (IG)

Yes

22

+++

No

−−

No

8

31

Solidb

Short fascicles

PSS (HG)

Yes

12

+++

Yes

+

No

9

19

Solidb

Short fascicles/Patternless

PSS (HG)

No

23

+++

Yes

−−

No

10

17

Solidb

Short fascicles

PSS (IG)

No

23

++

No

−−

No

11

69c

Solid

Patternless/Epithelioid

PSS (HG)

Yes

24

+++

No

++

Yes

  

Solid

Myxoid

STUMP

Yes

<1

+

No

+

Yes

12

78

Solidb (ESS-like)

Patternless

STUMP

No

<1

+++

No

−−

No

13

74

Phyllodes-like

Phyllodes

STUMP

Yes

<1

++

Yes

+

No

14

65

Solidb

Degenerative atypia

STUMP

No

<1

+

No

++

Yes

15d

64

Phyllodes-like

Phyllodes

STUMPd

Yes

<1

+

No

++

Yes

16

58

Phyllodes-like

Phyllodes

STUMP

Yes

<1

+

No

++

Yes

17

64

Phyllodes-like

Phyllodes

STUMP

Yes

<1

++

No

+

Yes

18

64

Solidb

Hypercellular

STUMP

No

1

++

No

−−

No

19

45

Solidb

Hypercellular

STUMP

No

2

++

No

−−

No

20

57

Solidb

Myxoid

STUMP

No

<1

+

Yes

+

Yes

21

69

Solidb

Myxoid

STUMP

No

<1

+

No

−−

No

22

56

Solidb

Hypercellular

STUMP

No

<1

+

No

−−

No

23

66

Solidb

Hypercellular

STUMP

No

<1

++

No

−−

No

24

71

Solidb

Hypercellular

STUMP

Yes

<1

+

No

−−

No

25

59

Phyllodes-like

Phyllodes

STUMP

Yes

<1

+

No

−−

No

  1. Symbols: −− = negative or minimal, + = mild, ++ = moderate, +++ = marked/severe.
  2. ABG associated with benign glands, ESS endometrial stromal sarcoma, HG high grade, IG intermediate grade, LG low grade, MTC multinucleate tumor cells, SC spindle cells, STUMP stromal tumor of uncertain malignant potential, PSS prostatic stromal sarcoma.
  3. aAs described by Herawi et al. [1].
  4. bDiffuse sheets of tumor cells with different architectural arrangements.
  5. cIn the manuscript, this case was counted as a PSS; therefore, only the histopathologic features of the PSS component were quantified.
  6. dThis case was initially diagnosed as STUMP, but later developed intraperitoneal metastases.
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