Fig. 1: Myxoid spindled cell whorls and cellular nodules. | Modern Pathology

Fig. 1: Myxoid spindled cell whorls and cellular nodules.

From: Superficial ALK-rearranged myxoid spindle cell neoplasm: a cutaneous soft tissue tumor with distinctive morphology and immunophenotypic profile

Fig. 1

A Myxoid areas with spindled cells arranged in a swirling pattern (case 2, 400×). B Alternating hypocellular myxoid areas with spindled cells arranged in whorls and cellular nodules consisting of plump spindled to ovoid cells (case 3, 200×). C, D Spindled cells arranged in tight concentric whorls in a myxoid stroma (C: case 5, 200×; D: case 6, 400×). E, F Myxohyaline areas with ovoid to spindled cells in cords and chains loosely packed in whorls (E: case 1, 200×; F: case 4, 400×). G, H More cellular areas of ovoid to plump spindle cells in loose aggregates. A moderate amount of tumor-infiltrating lymphocytes and plasma cells are present. (G: case 4; H: case 3; G, H: 400×). A–H: H&E.

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