Fig. 2: Biphasic appearance and special histologic features. | Modern Pathology

Fig. 2: Biphasic appearance and special histologic features.

From: Superficial ALK-rearranged myxoid spindle cell neoplasm: a cutaneous soft tissue tumor with distinctive morphology and immunophenotypic profile

Fig. 2

A–D Low power showing biphasic appearance of alternating hypocellular myxoid spindled cell areas and relatively cellular areas consisting of plump ovoid to epithelioid cells in aggregates and clusters (A: case 2, 200×; B: case 1, 100×; C: case 3, 200×; D: case 4, 100×). E Ectatic and hyalinized vasculature (case 4, 100×). F One case shows numerous linear to branching, thin-walled blood vessels (case 3, 200×). G, H Lipofibromatosis-like areas in the periphery with spindle cells interdigitating with adipocytes (G: case 3; H: case 4; G, H: 200×). A–H: H&E.

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