Fig. 5: Examples of mucinous adenocarcinoma and signet ring cell/poorly differentiated adenocarcinoma in our slide-level testing set.

An example of mucinous adenocarcinoma showed that our algorithm identified metastasis mainly based on viable tumor cells instead of mucin pools (a–d). An example of signet ring cell/poorly differentiated adenocarcinoma demonstrated that our algorithm identified metastasis mainly based on areas with higher density of tumor cells (e–h). Note that the areas with lower density of tumor cells were not highlighted.