Fig. 4: Association between overall survival in classic giant cell glioblastomas and glioblastomas with giant cell features based on molecular features. | Modern Pathology

Fig. 4: Association between overall survival in classic giant cell glioblastomas and glioblastomas with giant cell features based on molecular features.

From: SMARCAL1 loss and alternative lengthening of telomeres (ALT) are enriched in giant cell glioblastoma

Fig. 4

Kaplan–Meier curves and log rank tests demonstrate that there is not significant difference in overall survival based on A ATRX status (p = 0.08) or B SMARCAL1 status (p = 0.09); however, C there was a significantly better overall survival in patients with ALT-positive tumors compared to patients with ALT-negative tumors (p < 0.03).

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