Table 1 Additional somatic mutations in prostatic stromal tumors.

From: Reexamining the molecular findings in specialized stromal tumors of the prostate

#

Diagnosis

Gene

Alteration

SIFT

Poly-phen2

Allele fraction

dbSNP

Cosmic

Clinvar

c6

STUMP

KMT2D

c.A821C:p.K274T

T

D

0.56

rs894562087

  
  

POT1

c.T155G:p.V52G

D

D

0.39

rs200464979

COSM304691

 

c19

STUMP

KMT2D

c.C7144T:p.P2382S

D

P

0.48

rs3741626

COSM6494180

Benign

c21

STUMP

CHEK2

c.G1423C:p.E475Q

T

B

0.25

rs587782489

 

Uncertain

c22

STUMP

ATRX

c.G6212A:p.R2071K

T

D

0.2

   

c9

PSS

TP53

c.C59T:p.P20L

D

D

0.56

rs587782705

COSM10790

Pathogenic

  1. STUMP Stromal tumor of uncertain malignant potential, PSS prostatic stromal sarcoma, T tolerated, D damaging, P probably damaging, B benign.
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