Table 2 Pathologic features of patients with noninvasive BI EBV+ LBCL and breast implant ALCL (pT2).

From: Epstein–Barr-virus-positive large B-cell lymphoma associated with breast implants: an analysis of eight patients suggesting a possible pathogenetic relationship

Features

BI EBV+ LBCL, n = 7

Breast implant ALCL, n = 14

p value

Capsular thickness

   Median (µm, range)

2481 (1376–5700)

1120 (543–4347)

0.0439

Synovium-like lining

0/7 (0%)

3/14 (21%)

0.1859

Granular necrosis in lumen

7/7 (100%)

14/14 (100%)

>0.999

Layering of lymphoma cells

6/7 (86%)

3/14 (21%)

0.005

Hallmark cells

0/7 (0%)

10/14 (70%)

0.0039

Plasma cells

6/7 (86%)

9/14 (64%)

0.3055

Eosinophils

0/7 (0%)

4/14 (30%)

0.255

Outer capsule lymphoid aggregates

7/7 (100%)

0/14 (0%)

0.0001

Foamy histiocytes

2/7 (29%)

0/14 (0%)

0.0355

Silicone fragments

4/7 (58%)

11/14 (79%)

0.3055

Calcification in lumen

4/7 (58%)

1/14 (7%)

0.0112

  1. Bold p value indicates that comparison is statistically significant. Bold ratio and percentage indicate the value which is statistically significant.