Fig. 2: Morphological subtypes of poorly differentiated neuroendocrine carcinoma (original magnification, ×400).
From: Clinicopathological and genomic features in patients with head and neck neuroendocrine carcinoma
a, b Small cell carcinoma (a, SCC) and large cell neuroendocrine carcinoma (b, LCNEC). c, d Rb immunostaining for resected/biopsied specimens. Representative images of an Rb-positive specimen (c) and an Rb-deficient specimen (d) are shown (Rb antibody dilution, 1:100; original magnification, ×200). e Immunostaining for SMARCA4/BRG1 in the specimen harboring a SMARCA4 mutation (patient ID-11). BRG1 was lost in the tumor (SMARCA4/BRG1 antibody dilution, 1:100; original magnification, ×400).
