Fig. 4: Cellular angiofibroma. | Modern Pathology

Fig. 4: Cellular angiofibroma.

From: Potential pathogenetic link between angiomyofibroblastoma and superficial myofibroblastoma in the female lower genital tract based on a novel MTG1-CYP2E1 fusion

Fig. 4

A A well-demarcated and well-vascularized lesion (H&E). B A minor adipocytic component mainly in the peripheral area (H&E). C Bland-appearing spindle cells with an abundant fibrous stroma and dilated blood vessels exhibiting sclerotic walls (H&E). Immunohistochemical staining results highlighting (D) the loss of nuclear RB1 expression (nuclear positivity could be noted in the endothelial cells), (E) the lack of CYP2E1 expression in the tumor cells, and (F) mild MTG1 expression (scored as 1+) in the spindle cells and some inflammatory cells.

Back to article page