Table 2 Multivariate analysis for factors associated with disease-specific survival from the SEER database.
Clinicopathologic factors | HR (95% CI) | P value | Points assigned |
|---|---|---|---|
Age | |||
<50 years | Reference | 0 | |
≥50 years | 1.421 (1.326–1.521) | <0.0001 | 1 |
Race | |||
Caucasian | Reference | 0 | |
African American | 1.272 (1.185–1.365) | <0.0001 | 1 |
Other | 0.819 (0.738–0.909) | <0.0001 | 0 |
Unknown | 0.262 (0.118–0.583) | 0.001 | 0 |
Histologic grade | |||
I | Reference | 0 | |
II | 1.628 (1.440–1.840) | <0.0001 | 1 |
III | 2.516 (2.222–2.848) | <0.0001 | 1 |
Pathologic T stage | |||
T1 | Reference | 0 | |
T2 | 2.112 (1.934–2.308) | <0.0001 | 1 |
T3 | 3.343 (3.018–3.703) | <0.0001 | 1 |
T4 | 4.465 (4.043–4.930) | <0.0001 | 2 |
Pathologic N stage | |||
N0 | Reference | 0 | |
N1 | 1.376 (1.278–1.482) | <0.0001 | 1 |
N2 | 1.609 (1.467–1.764) | <0.0001 | 1 |
N3 | 1.884 (1.720–2.065) | <0.0001 | 1 |
M status | |||
M0 | Reference | 0 | |
M1 | 4. 842 (4.524–5.182) | <0.0001 | 2 |
ER status | |||
Positive | Reference | 0 | |
Negative | 1.468 (1.353–1.593) | <0.0001 | 1 |
PR status | |||
Positive | Reference | 0 | |
Negative | 1.542 (1.427–1.666) | <0.0001 | 1 |
HER2 status | |||
Positive | Reference | 0 | |
Negative | 1.698 (1.583–1.822) | <0.0001 | 1 |
