Fig. 4: Diagnostic workup of pleural effusion and small biopsy specimens with atypical mesothelial proliferations. | Modern Pathology

Fig. 4: Diagnostic workup of pleural effusion and small biopsy specimens with atypical mesothelial proliferations.

From: Pleural mesothelioma classification—update and challenges

Fig. 4

Initial immunohistochemical work-up to confirm mesothelial proliferation should be followed by markers of malignant mesothelial proliferations BAP1 immunohistochemistry and/or FISH for CDKN2A homozygous deletion or MTAP immunohistochemistry as surrogate marker (modified from ref. 30).

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