Fig. 2: Heterogeneity of immune markers in paired primary and metastatic tumors. | Modern Pathology

Fig. 2: Heterogeneity of immune markers in paired primary and metastatic tumors.

From: Heterogeneity of programmed death-ligand 1 expression and infiltrating lymphocytes in paired resected primary and metastatic non-small cell lung cancer

Fig. 2

A Heterogeneity in the tumor proportion score (TPS) of PD-L1 expression between paired primary tumors (PTs) and metastatic tumors (MTs). B Circos figure shows the increase and decrease in the continuous quantified value of TPS in different sites of metastases. C Circos figure shows the agreements of categorical TPS in MTs. D Heterogeneity in CD8+ cytotoxic T lymphocytes (CTLs) infiltration between paired PTs and MTs. E Circos figure shows the increase and decrease of CTLs infiltrating in MTs. F Heterogeneity in the spatial distance of CTLs and tumor cells (TCs) between paired PTs and MTs. G Schematic diagram illustrates the spatial distribution of the immune-to-tumor cell distances.

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