Fig. 2: Kappa concordance. | Modern Pathology

Fig. 2: Kappa concordance.

From: Digital validation of breast biomarkers (ER, PR, AR, and HER2) in cytology specimens using three different scanners

Fig. 2

(1) Kappa concordance of ER, PR, AR, and HER2 scores between all pathologist digital reads vs microscope. (2) Kappa concordance of ER, PR, and AR scores divided into groups between all scanners for pathologist B. (3) Kappa concordance of ER, PR, and AR scores divided into groups between all scanners for pathologist C. The p-value corresponds to a two-sided hypothesis test comparing reader-averaged accuracy with each scanner to the microscope and between scanners (0.41 to 0.60 moderate, 0.61 to 0.80 substantial, and 0.81 to 0.99 strong concordance). ER Estrogen Receptor, PR Progesterone Receptor, AR Androgen Receptor, HER2 Human Epidermal Growth Receptor 2.

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