Fig. 2: Invasive patterns of adenocarcinoma.
From: Updates in grading and invasion assessment in lung adenocarcinoma
A The acinar pattern is gland forming with large and small gland, with stromal change including desmoplasia. B The solid pattern is a confluence of cells without lumen formation. C Papillary adenocarcinoma is composed of arborizing structures with fibrovascular cores, with clover-like formations. D Micropapillary pattern of finger like stratifications without fibrovascular cores. E Micropapillary structures can be invasive with small clusters within spaces (retraction artefact). F Accumulations of small ring-like or radially oriented nuclei are one pattern of micropapillary. G Aggregates of cells with small lumen formation represent the complex glandular formation of cribriform pattern.
