Fig. 5: Challenges in distinction of acinar from lepidic pattern.
From: Updates in grading and invasion assessment in lung adenocarcinoma
A Small glandular profiles on the left alongside lepidic spaces support pattern change to invasion. B While both showing collapse and stromal change, increase in nuclear grade, cell shape and size from the area of the arrowhead to the arrow may support an acinar over lepidic pattern. C In addition to atypia, areas of transition to invasion often show greater stratification (arrowhead) than the lepidic pattern (arrows).
