Table 1 Characteristics of cases and controls. Age, sex, site of involvement, histological subtype and assessments performed in various groups.
From: Transcriptome and unique cytokine microenvironment of Castleman disease
Diagnosis | Age range in years (median) | M:F | Involvement | Subtype (n) | RNAseq:RNAISH:immunoseq assessment (n) |
|---|---|---|---|---|---|
UCD | 4–54(16.6) | 14:12 | Cervical-15 Mediastinal-5 Inguinal-2 Mesenteric-2 Axillary- 1 Soft tissue-1 | Hyaline vascular- 23 Mixed/Plasma cell -3 | 21:17:6 |
MCD | 12–71 (15) | 8:6 | Multiple sites | Plasma cell-8 TAFRO- 3 HIV-1 POEMS-2 | 12:8:8 |
Reactive | 2–48 (11) | 23:8 | Cervical-15 Mesenteric-4 Mediastinal-3 Axillary-5 Inguinal-2 Retroperitoneal-1 | Castleman like- 12 Follicular hyperplasia- 5 Infectious- 11 Dermatopathic-1 Sinus histiocytosis-2 | 35:11:5 |
