Table 2 Univariate and multivariate analysis of the EFS and OS of the patients in the training set.

From: BCL2 super-expressor diffuse large B-cell lymphoma: a distinct subgroup associated with poor prognosis

 

Univariate analysis

Multivariate analysis

HR (95% CI)

P value

HR (95% CI)

P value

EFS

  Male (vs. female)

1.470 (0.998–2.166)

0.051

1.489 (0.992–2.235)

0.055

  IPI 3–5 (vs. 0–2)

2.581 (1.768–3.767)

<0.001

2.357 (1.576–3.525)

<0.001

  Non-GCB (vs. GCB)

1.845 (1.223–2.782)

0.004

1.742 (1.149–2.640)

0.009

  Double expressor

2.062 (1.416–3.002)

<0.001

1.495 (0.997–2.243)

0.052

  BCL2 super-expressor

2.0176 (1.253–3.248)

0.004

1.903 (1.159–3.126)

0.011

OS

  Male (vs. female)

1.327 (0.873–2.016)

0.185

1.416 (0.914–2.193)

0.119

 IPI 3–5 (vs. 0–2)

3.216 (2.137–4.840)

<0.001

3.233 (2.120–4.930)

<0.001

  Non-GCB (vs. GCB)

1.873 (1.193–2.941)

0.006

1.823 (1.155–2.875)

0.01

  Double expressor

1.861 (1.235–2.805)

0.003

–

–

  BCL2 super-expressor

2.358 (1.437–3.868)

0.001

2.467 (1.474–4.127)

0.001

  1. EFS event-free survival, OS overall survival, IHC immunohistochemistry, COO cell of origin, GCB Germinal center B-cell like, IPI International Prognostic Index.
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