Table 1 Characteristics of classic Hodgkin lymphoma FFPE samples in study cohort.

From: Clonality assessment and detection of clonal diversity in classic Hodgkin lymphoma by next-generation sequencing of immunoglobulin gene rearrangements

Case

Diagnosis

Gender

Age at diagnosis (yr)

% HRS cells

% Total B cells

% HRS cells of total B cells

% T cells

EBV status

1

NSHL

M

14

5

40

11

20

Negative

2

NSHL

M

14

5

30

14

60

Negative

3

MCHL

F

14

5

25

17

40

Negative

4

NSHL

F

15

5

10

33

50

Negative

5

NSHL

F

17

5

15

25

30

Positive

6

NSHL

M

22

10

15

40

60

Negative

7

MCHL

M

22

1

30

3

60

Positive

8

NSHL

M

33

3

20

13

70

Positive

9

NSHL

M

38

3

10

23

80

Positive

10

MCHL

M

47

5

30

14

50

Negative

11

NSHL

M

76

5

10

33

60

Negative

12

NSHL

F

19

5

15

25

50

Negative

13

MCHL

M

44

2

20

9

50

Positive

14

MCHL

M

32

15

25

38

60

Negative

15

NSHL

M

61

3

25

11

40

Negative

16

NSHL

M

67

15

20

43

50

Positive

  1. The fraction of HRS cells, background B cells and T cells are estimated based on HE and CD30 (% HRS cells), CD79A (B cells), or CD2/CD3 (T cells) staining of FFPE tissue sections. Epstein-Barr virus (EBV) status was determined by Epstein-Barr encoding region (EBER) in situ hybridization. NSHL nodular sclerosis HL, MCHL mixed cellularity HL; yr years.