Fig. 2: Most of the tumors demonstrated the typical morphologic features of SDH-deficient RCC. | Modern Pathology

Fig. 2: Most of the tumors demonstrated the typical morphologic features of SDH-deficient RCC.

From: Expanding the clinicopathological spectrum of succinate dehydrogenase-deficient renal cell carcinoma with a focus on variant morphologies: a study of 62 new tumors in 59 patients

Fig. 2

They were well circumscribed, sometimes with a pseudocapsule separating them from the adjacent non-neoplastic kidney (A). Entrapped non-neoplastic tubules or glomeruli were a frequent finding (B). In some cases, the cells had dense eosinophilic cytoplasm (C), but in most instances (D, E) the cytoplasm was pale and flocculent, often with intracytoplasmic inclusions.

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