Fig. 6: Immuonohistochemistry for SDHB. | Modern Pathology

Fig. 6: Immuonohistochemistry for SDHB.

From: Expanding the clinicopathological spectrum of succinate dehydrogenase-deficient renal cell carcinoma with a focus on variant morphologies: a study of 62 new tumors in 59 patients

Fig. 6

Serial sections stained with hematoxylin and eosin (A, C) and SDHB IHC (B, D). Entrapped benign tubules were frequently seen at the edge of the tumors. SDHB IHC shows retained positive cytoplasmic staining in the internal controls (including entrapped benign tubules), but all the neoplastic cells are negative.

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