Table 3 Mean metallothionein IHC H-score by diagnosis.

From: Metallothionein immunohistochemistry has high sensitivity and specificity for detection of Wilson disease

Diagnosis

N

Mean H-score

Standard deviation

P value (for H-scores vs WD)a

Wilson disease

20

261.0

36.4

 

All control cases

203

13.6

29.8

<0.0001

   Normal liver

20

5.0

6.5

<0.0001

   Autoimmune hepatitis

50

13.8

27.3

<0.0001

   Chronic biliary tract disease

42

28.0

42.6

<0.0001

   Steatohepatitis

51

4.7

15.9

<0.0001

   Chronic hepatitis C

40

14.1

32.5

<0.0001

  1. aP value calculated with Wilcox–Mann–Whitney Test.
Back to article page