Table 4 Extent and intensity of metallothionein immunohistochemistry by diagnosis.
Diagnosis | N | Cases with any MT staining | Cases with >50% of hepatocytes staining (any intensity) | Cases with at least moderate MT staining in >50% of hepatocytes | Cases with strong intensity staining in >33% of hepatocytes |
|---|---|---|---|---|---|
Wilson disease | 20 | 20 (100%) | 20 (100%) | 20 (100%) | 15 (75%) |
All control cases | 203 | 75 (37%) | 18 (9%) | 0 (0%) | 0 (0%) |
Normal liver | 20 | 8 (40%) | 0 (0%) | 0 (0%) | 0 (0%) |
Autoimmune hepatitis | 50 | 22 (44%) | 5 (10%) | 0 (0%) | 0 (0%) |
Chronic biliary tract disease | 42 | 22 (52%) | 8 (19%) | 0 (0%) | 0 (0%) |
Steatohepatitis | 51 | 10 (20%) | 1 (2%) | 0 (0%) | 0 (0%) |
Chronic hepatitis C | 40 | 13 (33%) | 4 (10%) | 0 (0%) | 0 (0%) |