Fig. 1: Morphologic features of mast cell sarcoma (MCS).
From: Mast cell sarcoma: clinicopathologic and molecular analysis of 10 new cases and review of literature
A PET scan shows tumor involvement in L2 and paraspinal soft tissue. Two biopsies from the same location on patient #1 display (B) blastoid cytology with high N/C ratio, medium size, and fine chromatin and (C) sarcomatous features with scattered multinucleated giant tumor cells. D Histiocytoid tumor cells with frequent bi-lobated nuclei. E Large epithelioid cells with abundant cytoplasm and frequent eosinophils in the background. F Plasmacytoid or rhabdoid tumor cells with eccentric nuclei and abundant dense pink cytoplasm. (B–F, H&E, ×400).
