Table 4 Immunohistochemical stains and KIT status of mast cell sarcoma.

From: Mast cell sarcoma: clinicopathologic and molecular analysis of 10 new cases and review of literature

 

Our study (n = 10)

Literature (n = 24)

Combined (n = 34)

CD2

1/9

7/15

8/24 (33%)

CD25

4/9

11/16

15/25 (60%)

CD117

10/10

22/22

32/32 (100%)

Mast cell tryptase

10/10

22/22

32/32 (100%)

CD1a

0/5

0/5

0/10 (0%)

CD3

0/8

0/11

0/19 (0%)

CD4

2/5

2/3

4/8 (50%)

CD13

3/3

4/4

7/7 (100%)

CD20

0/7

0/8

0/15 (0%)

CD30

5/8

8/16

13/24 (54%)

CD33

10/10

5/5

15/15 (100%)

CD34

0/8

0/12

0/20 (0%)

CD43

8/8

6/6

14/14 (100%)

CD45

5/9

8/11

13/20 (65%)

CD56

2/5

1/3

3/8 (38%)

CD68

5/9

13/13

18/22 (82%)

CD123

2/3

1/3

3/6 (50%)

CD163

0/6

0/3

0/9 (0%)

MPO

0/7

0/10

0/17 (0%)

S100

0/10

0/7

0/17 (0%)

Overall KIT mutations

2/9

6/19

8/28 (29%)

KIT D816V mutation

0/9

2/19

2/28 (7%)