Fig. 2: Representative histopathological images of primary metaplastic carcinoma and subsequent metastases in patient 2.
From: Genomic characterization and tumor evolution in paired samples of metaplastic breast carcinoma
Primary metaplastic carcinoma with squamous differentiation (A). Local recurrence of metaplastic squamous cell carcinoma with abundant keratinization and marked nuclear atypia (B). Metastatic metaplastic squamous cell carcinoma in cranial vault infiltrating cerebral tissue (C). Metastatic metaplastic spindle cell carcinoma of the skull featuring high-grade spindled cells and abundant mitoses (D). Scale bars equal 50 μm on (A, B, and D), and 100 μm on (C).
